{"product_id":"abcam-ab144327","title":"Abcam, ab144327, Cyclic Pifithrin-alpha hydrobromide, pifithrin-alpha analog","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 349.3 Da, Purity \u0026gt;98%. Stable, cell-permeable analog of pifithrin-α (ab120478). Inhibits p53-mediated apoptosis and p53-dependent gene transcription. Prevents dexamethasone-induced cell death in murine thymocytes (EC 50  = 2.01 μM). Potent STAT6 transcriptional inhibitor. Active  in vivo  and  in vitro . See similar compound .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:511296-88-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:349.3 Da,\u003cbr\u003e\nMolecular formula:C16H17BrN2S,\u003cbr\u003e\nPubChem:11515812,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:Pifithrin-beta hydrobromide,\u003cbr\u003e\nBiological description:Stable, cell-permeable analog of pifithrin-α (ab120478). Inhibits p53-mediated apoptosis and p53-dependent gene transcription. Prevents dexamethasone-induced cell death in murine thymocytes (EC50 = 2.01 μM). Potent STAT6 transcriptional inhibitor. Active in vivo and in vitro.See similar compound,\u003cbr\u003e\nCanonical smiles:CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2.Br,\u003cbr\u003e\nInChi:InChI=1S\/C16H16N2S.BrH\/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;\/h6-10H,2-5H2,1H3;1H,\u003cbr\u003e\nInChiKey:SGNCOAOESGSEOP-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole;hydrobromide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847477612713,"sku":"ab144327","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144327","provider":"Iright","version":"1.0","type":"link"}