{"product_id":"abcam-ab144422","title":"Abcam, ab144422, CAY10585, HIF-1alpha inhibitor","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 25mg\u003cbr\u003e\nMW 435.5 Da, Purity \u0026gt;97%. HIF-1α inhibitor (IC 50  values are 2.6 and 0.7 μM for Hep3B and AGS cell lines respectively). Suppresses transcription of HIF-1 target genes VEGF and erythropoietin at 10 μM. Attenuates hypoxia-induced ANP secretion. Blunts BMP9-induced osteogenic signaling in MSCs.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:934593-90-5,\u003cbr\u003e\nPurity:\u0026gt;97%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:435.5 Da,\u003cbr\u003e\nMolecular formula:C26H29NO5,\u003cbr\u003e\nPubChem:35028748,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 10 mM,\u003cbr\u003e\nBiochemical name:3-[[2-[4-(2-Adamantyl)phenoxy]-1-oxoethyl]amino]-4-hydroxybenzoic acid methyl ester,\u003cbr\u003e\nBiological description:HIF-1α inhibitor (IC50 values are 2.6 and 0.7 μM for Hep3B and AGS cell lines respectively). Suppresses transcription of HIF-1 target genes VEGF and erythropoietin at 10 μM. Attenuates hypoxia-induced ANP secretion. Blunts BMP9-induced osteogenic signaling in MSCs.,\u003cbr\u003e\nCanonical smiles:COC(=O)C1=CC(=C(C=C1)O)NC(=O)COC2=CC=C(C=C2)C3C4CC5CC(C4)CC3C5,\u003cbr\u003e\nInChi:InChI=1S\/C26H29NO5\/c1-31-26(30)18-4-7-23(28)22(13-18)27-24(29)14-32-21-5-2-17(3-6-21)25-19-9-15-8-16(11-19)12-20(25)10-15\/h2-7,13,15-16,19-20,25,28H,8-12,14H2,1H3,(H,27,29),\u003cbr\u003e\nInChiKey:CSCOJWVRGOZGPK-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:methyl 3-[[2-[4-(2-adamantyl)phenoxy]acetyl]amino]-4-hydroxybenzoate\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847423807657,"sku":"ab144422","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144422","provider":"Iright","version":"1.0","type":"link"}