{"product_id":"abcam-ab144542","title":"Abcam, ab144542, TLCK (Tosyl-L-lysyl-chloromethane hydrochloride), Trypsin inhibitor","description":"\u003cp\u003eSize: 200mg\u003cbr\u003e\nMW 369.3 Da, Purity \u0026gt;95%. Irreversible inhibitor of trypsin and trypsin-like serine proteases. Blocks LPS- or cytokine-induced NF-κB activation. Inhibits caspase processing; blocks apoptosis. Active  in vitro  and  in vivo .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:4272-74-6,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:369.3 Da,\u003cbr\u003e\nMolecular formula:C14H22Cl2N2O3S,\u003cbr\u003e\nPubChem:73093,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in methanol (50mg\/mL)Soluble in DMSO (5mM)Soluble in water. Stock solutions up to 10mM can be prepared in aqueous buffers with pH 6.0 or lower.,\u003cbr\u003e\nBiochemical name:N-alpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride,\u003cbr\u003e\nBiological description:Irreversible inhibitor of trypsin and trypsin-like serine proteases. Blocks LPS- or cytokine-induced NF-κB activation. Inhibits caspase processing; blocks apoptosis. Active in vitro and in vivo.,\u003cbr\u003e\nCanonical smiles:CC1=CC=C(C=C1)S(=O)(=O)NC(CCCCN)C(=O)CCl.Cl,\u003cbr\u003e\nIsomeric smiles:CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C14H21ClN2O3S.ClH\/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;\/h5-8,13,17H,2-4,9-10,16H2,1H3;1H\/t13-;\/m0.\/s1,\u003cbr\u003e\nInChiKey:YFCUZWYIPBUQBD-ZOWNYOTGSA-N,\u003cbr\u003e\nIUPAC Name:N-[(3S)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide;hydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product has been reported to be very unstable in solutions with a pH above 6, at 25\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847417155753,"sku":"ab144542","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144542","provider":"Iright","version":"1.0","type":"link"}