{"product_id":"abcam-ab145231","title":"Abcam, ab145231, IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide), Necrosis inhibitor","description":"\u003cp\u003eSize: 1mg\u003cbr\u003e\nMW 325.4 Da, Purity \u0026gt;98%. Potent, selective necrosis inhibitor (IC 50  = 3 μM, H 2 O 2  exposed HeLa cells). Reduces oxidative stress-induced necrosis without effecting anticancer drug-induced apoptosis. Inhibits oxidative stress-induced necrotic cell death  in vivo.  .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:861891-50-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:325.4 Da,\u003cbr\u003e\nMolecular formula:C19H23N3O2,\u003cbr\u003e\nPubChem:16760577,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione,\u003cbr\u003e\nBiological description:Potent, selective necrosis inhibitor (IC50 = 3 μM, H2O2 exposed HeLa cells). Reduces oxidative stress-induced necrosis without effecting anticancer drug-induced apoptosis. Inhibits oxidative stress-induced necrotic cell death in vivo.,\u003cbr\u003e\nCanonical smiles:CCCCCNC1=C(C(=O)N(C1=O)C)C2=CN(C3=CC=CC=C32)C,\u003cbr\u003e\nInChi:InChI=1S\/C19H23N3O2\/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15\/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3,\u003cbr\u003e\nInChiKey:SGLOMINNEBLJFF-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847485345961,"sku":"ab145231","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab145231","provider":"Iright","version":"1.0","type":"link"}