{"product_id":"abcam-ab145601","title":"Abcam, ab145601, MDL 28170 (Calpain Inhibitor III), calpain and cathepsin B inhibitor","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 382.5 Da, Purity \u0026gt;95%. Potent and selective cell-permeable calpain and cathepsin B inhibitor (IC 50  = 11 nM, calpain, K i  values are 10 and 25 nM for calpain and cathepsin B respectively). Shows neuroprotective effects  in vivo . Blood-brain barrier permeable.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:88191-84-8,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nMolecular weight:382.5 Da,\u003cbr\u003e\nMolecular formula:C22H26N2O4,\u003cbr\u003e\nPubChem:9907994,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:Z-Val-Phe-CHO,\u003cbr\u003e\nBiological description:Potent and selective cell-permeable calpain and cathepsin B inhibitor (IC50 = 11 nM, calpain, Ki values are 10 and 25 nM for calpain and cathepsin B respectively). Shows neuroprotective effects in vivo. Blood-brain barrier permeable.,\u003cbr\u003e\nCanonical smiles:CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2,\u003cbr\u003e\nInChi:InChI=1S\/C22H26N2O4\/c1-16(2)20(24-22(27)28-15-18-11-7-4-8-12-18)21(26)23-19(14-25)13-17-9-5-3-6-10-17\/h3-12,14,16,19-20H,13,15H2,1-2H3,(H,23,26)(H,24,27),\u003cbr\u003e\nInChiKey:NGBKFLTYGSREKK-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:benzyl N-[3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 2195 MDL 28170. 2195-50 is the same size as the 50 mg size of ab145601.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions|The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847427805353,"sku":"ab145601","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab145601","provider":"Iright","version":"1.0","type":"link"}