{"product_id":"abcam-ab146825","title":"Abcam, ab146825, CRT5, protein kinase D inhibitor","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 454.6 Da, Purity \u0026gt;97%. Potent, selective, pyrazine benzamide protein kinase D inhibitor (IC 50  values are 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3 respectively). Blocks phosphorylation of PKD1 on Ser 916  and PKD2 on Ser 876 , but does not affect PKC-dependent PKD phosphorylation. Decreases VEGF-induced endothelial migration, proliferation and tubulogenesis.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1034297-58-9,\u003cbr\u003e\nPurity:\u0026gt;97%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:454.6 Da,\u003cbr\u003e\nMolecular formula:C28H30N4O2,\u003cbr\u003e\nPubChem:58238286,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 50 mM,\u003cbr\u003e\nBiochemical name:Crt5 (crt0066051),\u003cbr\u003e\nBiological description:Potent, selective, pyrazine benzamide protein kinase D inhibitor (IC50 values are 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3 respectively). Blocks phosphorylation of PKD1 on Ser916 and PKD2 on Ser876, but does not affect PKC-dependent PKD phosphorylation. Decreases VEGF-induced endothelial migration, proliferation and tubulogenesis.,\u003cbr\u003e\nCanonical smiles:CCOC1=CC2=C(C=C1)C=C(C=C2)C3=C(N=CC(=C3)C4=CC(=CC=C4)C(=O)NCCN(C)C)N,\u003cbr\u003e\nInChi:InChI=1S\/C28H30N4O2\/c1-4-34-25-11-10-20-14-22(9-8-21(20)16-25)26-17-24(18-31-27(26)29)19-6-5-7-23(15-19)28(33)30-12-13-32(2)3\/h5-11,14-18H,4,12-13H2,1-3H3,(H2,29,31)(H,30,33),\u003cbr\u003e\nInChiKey:XBDRAUPLGHAFCU-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:3-[6-amino-5-(6-ethoxynaphthalen-2-yl)pyridin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847482626217,"sku":"ab146825","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab146825","provider":"Iright","version":"1.0","type":"link"}