{"product_id":"abcam-ab146829","title":"Abcam, ab146829, Compound 6877002, CD40-TRAF6 interaction inhibitor","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 251.33 g\/mol, Purity \u0026gt;99%. CD40-TRAF6 interaction inhibitor. Small molecule that binds to TRAF6, blocking interactions with CD40. Suppresses CD40-induced IL-1β and IL-6 expression in primary macrophages  in vitro . Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in a mouse diet-induced obesity model.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:433249-94-6,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:251.33 g\/mol,\u003cbr\u003e\nMolecular formula:C17H17NO,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in ethanol to 100 mMSoluble in DMSO to 100mM,\u003cbr\u003e\nBiological description:CD40-TRAF6 interaction inhibitor. Small molecule that binds to TRAF6, blocking interactions with CD40. Suppresses CD40-induced IL-1β and IL-6 expression in primary macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in a mouse diet-induced obesity model.,\u003cbr\u003e\nIsomeric smiles:CC2CC(N\/C=C\/C(=O)C1CCCCC1)C(C)CC2,\u003cbr\u003e\nInChi:InChI=1\/C17H17NO\/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15\/h3-12,18H,1-2H3\/b11-10+,\u003cbr\u003e\nInChiKey:SARYOFMRLSHZFE-ZHACJKMWNA-N,\u003cbr\u003e\nIUPAC Name:3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847448613033,"sku":"ab146829","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab146829","provider":"Iright","version":"1.0","type":"link"}