{"product_id":"abcam-ab150353","title":"Abcam, ab150353, Anti-RBMS1 antibody [EPR9825(B)]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal RBMS1 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 7 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR9825(B),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRBMS1 or RNA-binding motif single-stranded interacting protein 1 is a protein that plays an important role in binding single-stranded RNA and DNA. It has a molecular mass of approximately 45 kDa and is widely expressed in various tissues including but not limited to the brain liver and heart. Functionally RBMS1 contributes to a range of cellular processes by regulating the stability and translation of its bound nucleic acids.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe RNA-binding capabilities of RBMS1 enable it to exert influence over gene expression and cellular proliferation. RBMS1 interacts with multiple other proteins becoming part of larger complexes that facilitate its regulatory actions. Complex formation with diverse molecular partners allows RBMS1 to influence different aspects of RNA metabolism and stability impacting cellular growth and development.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe involvement of RBMS1 is notable in pathways regulating cell cycle and apoptosis. RBMS1 associates with components of the cell cycle control machinery affecting checkpoint regulation and cell proliferation. Its interaction with proteins like MYC and other cell cycle pathogenic elements highlights its role in the fine-tuning of growth-related cascades and programmed cell death mechanisms.\u003cbr\u003e\nRBMS1 is associated with certain types of cancer notably those where gene expression misregulation is a factor. Altered expression or mutation of RBMS1 may contribute to oncogenic processes alongside proteins such as KRAS facilitating tumor progression and metastasis. Furthermore RBMS1 dysregulation can influence neurological disorders possibly through pathways that involve cell death such as those linked to neurodegenerative disease markers.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850281799849,"sku":"ab150353","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab150353","provider":"Iright","version":"1.0","type":"link"}