{"product_id":"abcam-ab159283","title":"Abcam, ab159283, Recombinant Human Thymosin alpha 1 protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human Thymosin alpha 1 protein is a Human Full Length protein, in the 1 to 110 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:P06454,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThymosin alpha 1 also known as Tα1 is a peptide with a molecular weight of approximately 3108 Daltons. It is expressed within the thymus an organ critical for T cell maturation. Structurally Tα1 consists of 28 amino acid residues and functions through interactions with the immune cells. As a result it engages in various roles to stimulate immune responses and bolster the body's defense mechanisms against pathogens.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThymosin alpha 1 stimulates the maturation and differentiation of T cells central players in the adaptive immune response. It organizes these cells to enhance their capability to recognize antigens and react to infections or abnormal cells. Thymosin alpha 1 does not form part of any known larger complexes but independently precipitates a cascade of immune-related activities. These actions establish thymosin alpha 1 as an important regulatory molecule in the immune system.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe biological function of thymosin alpha 1 is integrated into the immune response pathways. It is notably involved in the T cell receptor signaling pathway contributing to the activation and proliferation of T cells. Thymosin alpha 1 associates closely with proteins such as interleukin-2 and interferon-alpha which are critical to these immune pathways. Together these molecules reinforce the immune defense by promoting cell-mediated immunity in the presence of antigens.\u003cbr\u003e\nThymosin alpha 1 shows relevance to infectious diseases including hepatitis B and C where it supports antiviral responses. It also displays therapeutic potential in cancer treatment enhancing the efficacy of certain therapies. Moreover thymosin alpha 1 interacts with proteins like interleukin-2 in these disease contexts working to improve immune surveillance and control malignant cell growth and viral spread.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843970322601,"sku":"ab159283","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab159283","provider":"Iright","version":"1.0","type":"link"}