{"product_id":"abcam-ab162570","title":"Abcam, ab162570, Recombinant Human VCX-A protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human VCX-A protein is a Human Full Length protein, in the 1 to 166 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q9NNX9,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product was previously labelled as VCX3A.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nVCX-A also known as Variably Charged X-linked protein A is part of a family of proteins that share a similar motif. It weighs approximately 15 kDa. VCX-A is mostly expressed in the testis specifically in germ cells suggesting a role in male reproduction. It is found in specific tissues with minimal expression in other organs which indicates its specialized function.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe protein belongs to a group known for its involvement in cell cycle regulation indicating it may influence spermatogenesis. While detailed interactions of VCX-A remain under study its relation to the Variably Charged X-linked (VCX) protein family suggests it may form complexes to act as a modulator within cells. This regulation may involve phosphorylation states impacting how germ cells progress through developmental phases.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe Variably Charged X-linked protein family takes part in cellular mechanisms ensuring proper cell division. In particular VCX-A might be associated with the regulation of the spermatogenic process and cell cycle checkpoints. It could interact with proteins linked to the regulation pathway of cyclins and cyclin-dependent kinases which play an essential role in cell cycle progression hinting at a connection with proteins like CDC25A.\u003cbr\u003e\nVCX-A expression or dysfunction could potentially link to infertility due to abnormal germ cell development. Aberrations in proteins similar to VCX-A might also imply a connection with testicular dysgenesis syndrome. The protein's interaction with other members of its family or related regulatory proteins such as those involved in chromatin organization suggests a pathway potentially sensitive to malfunction contributing to these conditions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843959607465,"sku":"ab162570","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab162570","provider":"Iright","version":"1.0","type":"link"}