{"product_id":"abcam-ab163873","title":"Abcam, ab163873, Recombinant Human S100P binding protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human S100P binding protein is a Human Full Length protein, in the 1 to 408 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q96BU1,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe S100P binding protein also called S100PB interacts directly with S100P a member of the S100 family of calcium-binding proteins. This protein has a molecular mass of approximately 40 kDa. It is present in various tissues and organs including the placenta and certain types of epithelial tissues. The protein's expression varies and changes in its expression levels often correlate with different physiological and pathological conditions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nS100PB modulates the activity of S100P by binding to it which influences several cellular functions. It does not function as a standalone protein but is instead part of complexes that affect cellular signaling proliferation and differentiation. This interaction can impact cellular processes such as cell growth and apoptosis hinting at roles in cellular proliferation mechanisms and stress responses.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe S100P binding protein is associated with the regulation of cellular responses to external stressors and intracellular signal transduction pathways. It plays a role in the MAPK\/ERK pathway and might influence the activity of proteins like Raf and MEK. These pathways are critical for intracellular communication that controls cell division differentiation and development. The protein interactions and binding activities show its significance within these cellular signaling frameworks.\u003cbr\u003e\nS100P binding protein involvement has been noted in cancer progression and metastasis as well as inflammatory diseases. In cancer it interacts with and possibly regulates other S100 proteins contributing to processes that facilitate tumor growth and spread. Its role in inflammation may include modulating inflammatory responses linked to the activities of proteins involved in immune regulation. The connection with these disorders makes it a potential target for therapeutic interventions given its influence on cellular signaling and disease-related pathways.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843936014505,"sku":"ab163873","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab163873","provider":"Iright","version":"1.0","type":"link"}