{"product_id":"abcam-ab168370","title":"Abcam, ab168370, Anti-GAS-7 antibody [EPR11129(B)]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal GAS-7 antibody. Suitable for IHC-P, WB, ICC\/IF and reacts with Human, Mouse, Rat samples. Cited in 2 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR11129(B),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:WB, IHC-P, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nGrowth Arrest-Specific 7 often known as GAS7 is a protein with a molecular weight of approximately 48 kDa. GAS7 is known for its expression in neural tissues particularly in the brain where it plays an important role in cellular processes. This protein participates in the growth arrest of cells specifically in neurons indicating its importance in neurological functions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nGAS7 contributes to the regulation of neuronal development and morphology. It is a part of various cellular complexes that guide the proper formation and differentiation of neurons. Studies show it helps in the development of the nerve cell cytoskeleton which is critical for maintaining neuronal architecture and function.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe involvement of GAS7 includes those related to cytoskeletal organization and neuronal differentiation. Two significant pathways include the MAPK signaling pathway and the PI3K-Akt signaling pathway. GAS7 interacts with other proteins such as actin and filamin which are essential components in these pathways to regulate cell shape and motility.\u003cbr\u003e\nGAS7 is linked to certain neurological conditions like neurodegenerative disorders and developmental issues. Abnormalities in GAS7 expression or function may have connections to disorders like Alzheimer's disease where cytoskeletal anomalies are common. Additionally its interaction with the protein tau which is implicated in Alzheimer's highlights its potential role in the manifestation of such diseases.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844184101033,"sku":"ab168370","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab168370","provider":"Iright","version":"1.0","type":"link"}