{"product_id":"abcam-ab175219","title":"Abcam, ab175219, Anti-RPS12 antibody [EPR10963]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal RPS12 antibody. Suitable for IP, WB, ICC\/IF, Flow Cyt (Intra) and reacts with Human, Mouse, Rat samples. Cited in 3 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR10963,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:ICC\/IF, Flow Cyt (Intra), IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRPS12 also known as Ribosomal Protein S12 is a component of the 40S ribosomal subunit. It has a molecular mass of approximately 14 kDa. This protein plays an important role in the synthesis of proteins by helping to translate messenger RNA into polypeptides. It is expressed widely in human tissues indicating its fundamental role in cellular function. RPS12 is an integral part of ribosome structure and functionality contributing to the assembly and stability of the ribosomes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nRibosomal Protein S12 is involved in forming the small ribosomal subunit and it is a part of the ribonucleoprotein complex that is responsible for decoding genetic information. This complex ensures the accurate translation of genetic sequences which is essential for proper cell division and growth. The function of RPS12 extends to maintaining the fidelity of translation ensuring that amino acids are added correctly during protein synthesis.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe role of Ribosomal Protein S12 is significant in the mRNA translation pathway affecting gene expression and protein production. It is directly linked to the regulation of the translation machinery. RPS12 is associated with various other ribosomal proteins such as RPS6 and RPL5 to form a coordinated network that influences protein synthesis and cellular responses to environmental changes. Its interaction with these proteins underpins its participation in the global control of protein synthesis.\u003cbr\u003e\nAltered expression or mutations in Ribosomal Protein S12 have connections with certain ribosomopathies. Disorders like Diamond-Blackfan anemia relate to dysfunctions within ribosomal components including RPS12. Moreover aberrations in ribosomal proteins including RPS12 can predispose individuals to cancer by disrupting normal cell growth control. Understanding how RPS12 interacts with proteins involved in these diseases can provide insights into potential therapeutic targets.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850332197033,"sku":"ab175219","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab175219","provider":"Iright","version":"1.0","type":"link"}