{"product_id":"abcam-ab176708","title":"Abcam, ab176708, Anti-ZNF316 antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal ZNF316 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF316 aa 450-550.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human ZNF316 aa 450-550. The exact immunogen used to generate this antibody is proprietary information.A6NFI3\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab176708 was affinity purified using an epitope specific to ZNF316 immobilized on solid support., Storage buffer-pH: 6.8 - 7.4Preservative: 0.09% Sodium azideConstituents: 99% Tris buffered saline, 0.1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nZNF316 also known as Zinc Finger Protein 316 acts as a transcription factor involved in regulating gene expression. It possesses multiple C2H2-type zinc fingers that allow it to bind specifically to DNA sequences influencing transcriptional activity. The protein has an approximate mass of 70 kDa based on sequence data analysis. ZNF316 is expressed in various tissues with notable expression in the brain and reproductive organs suggesting its role in diverse physiological processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nZinc finger proteins like ZNF316 contribute to protein-DNA interactions that regulate gene transcription. This protein may interact with other transcriptional regulators to modulate gene expression patterns essential for cell differentiation and development. While ZNF316 has not been documented as part of a well-characterized multi-protein complex its zinc finger domains suggest a potential for forming interactions with co-regulatory proteins or elements influencing chromatin structure.\u003cbr\u003e\nPathways\u003cbr\u003e\nZNF316 has a role in the transcriptional regulation within pathways related to neural development and reproductive function. Specifically it appears involved in pathways with genes that are critical for signaling in neural tissue and may interact functionally within the Wnt signaling cascade. This interaction can link it to proteins such as β-catenin although further research may clarify additional pathway-specific interactions.\u003cbr\u003e\nScientific studies suggest a relationship between ZNF316 and neurological conditions such as schizophrenia. Aberrations in the expression or function of ZNF316 may contribute to pathogenesis potentially due to disrupted gene regulatory mechanisms in the brain. Furthermore gastrointestinal cancers have been linked to dysregulation in ZNF316 expression or activity possibly involving its interaction with tumor suppressor proteins like p53 therefore affecting cell proliferation and apoptosis. Continued research is necessary to elucidate these associations in greater detail.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854023643305,"sku":"ab176708","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab176708","provider":"Iright","version":"1.0","type":"link"}