{"product_id":"abcam-ab180856","title":"Abcam, ab180856, Anti-AWP1 antibody [EPR12323]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal AWP1 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR12323,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nAWP1 also known as AWP1 or AWP1 protein functions mechanically as an adapter molecule involved in various cellular processes. This protein is approximately 36 kDa in mass. AWP1 is expressed throughout many tissues including the heart liver and kidney. Its expression reflects the diverse roles it plays across different cellular environments where it modulates interactions between proteins.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nAWP1 participates in the regulation of signaling pathways and cellular communication. It acts as part of a protein complex that facilitates the interaction between membrane proteins and cytosolic components. AWP1's role in modulating these interactions is important for maintaining normal cellular activities impacting processes such as cell proliferation and apoptosis.\u003cbr\u003e\nPathways\u003cbr\u003e\nAWP1 plays roles in the signaling and immune pathways. It influences the NF-kB signaling pathway an important pathway involved in immune response and inflammation. AWP1 interacts with proteins like TRAF6 impacting the cascade of signaling events that regulate cellular responses to external stimuli. Additionally it participates in pathways related to cellular stress responses integrating signals that dictate cell survival.\u003cbr\u003e\nAWP1 associates with conditions like inflammation and cancer. In certain cancers dysregulated AWP1 expression is connected to abnormal cell proliferation and survival. The protein interacts with other key players like PI3K which contribute to oncogenic processes in cancer. In inflammatory disorders AWP1's role in modulating NF-kB signaling can lead to altered immune responses potentially exacerbating disease severity.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46860630360233,"sku":"ab180856","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab180856","provider":"Iright","version":"1.0","type":"link"}