{"product_id":"abcam-ab181187","title":"Abcam, ab181187, Anti-SPAG7 antibody [EPR13391]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal SPAG7 antibody. Suitable for IP, WB, ICC\/IF and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR13391,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, ICC\/IF, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nSPAG7 also known as Sperm Associated Antigen 7 is a protein with an approximate mass of 26 kilodaltons. It is mainly expressed in the testis with additional expression noted in other tissues at lower levels. Mechanically SPAG7 functions in the regulation of cellular processes associated with spermatogenesis playing a role in the assembly and reorganization of microtubule structures.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nSPAG7 enhances the development and function of sperm cells contributing significantly to male fertility. The protein participates in microtubule-related activities and likely interacts with other proteins to perform its roles effectively. Research suggests that SPAG7 does not form a complex on its own but it closely associates with other cellular components in sperm maturation.\u003cbr\u003e\nPathways\u003cbr\u003e\nSPAG7 interacts with regulatory networks involved in cilia and flagella movement contributing to the sperm's motility. SPAG7 shows a relationship with proteins like dynein and kinesin which are important in microtubule dynamics and cellular transport processes. It plays a part in pathways such as the spermatogenesis pathway where it ensures proper function and motility of sperm cells through its interactions with other proteins.\u003cbr\u003e\nSPAG7 has associations with male infertility which is often linked to defective spermatogenesis and sperm motility issues. Abnormal SPAG7 expression may disrupt cellular transport processes causing infertility. Although not directly implicated in diseases like cancer alterations in SPAG7 levels could potentially influence cancer-associated proteins through indirect pathways reflecting complex biological interactions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850406383785,"sku":"ab181187","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab181187","provider":"Iright","version":"1.0","type":"link"}