{"product_id":"abcam-ab181933","title":"Abcam, ab181933, Recombinant Human OXLD1 protein","description":"\u003cp\u003eSize: 20µg\u003cbr\u003e\nRecombinant Human OXLD1 protein is a Human Fragment protein, in the 46 to 147 aa range, expressed in Escherichia coli, with \u0026gt;90%, suitable for SDS-PAGE, Mass Spec.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;90% SDS-PAGE,\u003cbr\u003e\nExpression system:Escherichia coli,\u003cbr\u003e\nTags:His tag N-Terminus,\u003cbr\u003e\nApplications:SDS-PAGE, Mass SpecSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q5BKU9,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nOXLD1 also known as oxidoreductase-like domain 1 acts as an oxidoreductase enzyme that plays a role in catalyzing electron transfer reactions. The protein has a molecular mass of approximately 35 kDa and is expressed in various tissues but shows higher levels in liver and kidney cells. The structure of OXLD1 facilitates its involvement in redox reactions impacting several biochemical processes within these tissues.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe enzymatic activity of OXLD1 influences cellular redox homeostasis impacting cellular metabolism and signaling. OXLD1 actively participates in a protein complex that modulates redox-sensitive transcription factors affecting gene expression linked to oxidative stress responses. This function highlights its role in maintaining cellular balance and adapting cellular activities in response to stress factors.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe activities of OXLD1 integrate into the oxidative phosphorylation and glycolysis pathways influencing energy production and metabolism. In oxidative phosphorylation OXLD1 interacts with the NADH dehydrogenase complex which plays a significant part in the electron transport chain. Through these interactions OXLD1 establishes a regulatory connection with other proteins like NADH dehydrogenase contributing to ATP production and metabolic regulation.\u003cbr\u003e\nOXLD1 shows relevance to conditions involving oxidative stress and metabolic imbalance such as diabetes and atherosclerosis. Research indicates interaction of OXLD1 with superoxide dismutase a protein involved in detoxifying reactive oxygen species. These interactions suggest a potential role in influencing the development and progression of these disorders. Understanding how OXLD1 functions in these contexts may aid in developing therapeutic strategies targeting oxidative stress-related pathologies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844004106409,"sku":"ab181933","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab181933","provider":"Iright","version":"1.0","type":"link"}