{"product_id":"abcam-ab188442","title":"Abcam, ab188442, Anti-TMEM56 antibody - C-terminal","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal TMEM56 antibody. C-terminal. Suitable for IHC-P, ICC\/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-P, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q96MV1\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nTMEM56 also known as Transmembrane Protein 56 has a mass of approximately 43 kDa. It functions as a transmembrane protein that spans the cell membrane. The protein participates in cellular signaling by allowing or facilitating interaction across the membrane. TMEM56 is expressed in various tissues including the lungs heart and placenta. Its membrane-spanning capabilities suggest a role in linking extracellular signals to intracellular responses.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe role of TMEM56 involves regulation of cellular growth and differentiation processes. It may also interact with other membrane-associated proteins as part of the cellular response complex. By engaging in these processes TMEM56 influences important cellular dynamics that maintain tissue homeostasis and proper cellular function.\u003cbr\u003e\nPathways\u003cbr\u003e\nTMEM56 integrates into signal transduction pathways associated with cellular proliferation and differentiation. It participates in the MAPK\/ERK pathway which is important for transmitting extracellular signals into cellular responses. In this context TMEM56 interacts with components like MEK and ERK influencing cell fate decisions and responses to external stimuli.\u003cbr\u003e\nTMEM56 shows an association with certain types of cancer particularly in its involvement in deregulated cell signaling. Alterations in TMEM56 expression levels or function can disrupt normal cellular signaling contributing to oncogenic processes. Additionally altered expression of TMEM56 connects to neurodegenerative disorders possibly through pathways shared with proteins like Tau which is implicated in conditions like Alzheimer’s disease.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850146762921,"sku":"ab188442","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab188442","provider":"Iright","version":"1.0","type":"link"}