{"product_id":"abcam-ab206914","title":"Abcam, ab206914, Anti-BTG4 antibody [EPRZJU-21]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal BTG4 antibody. Suitable for IP, WB, ICC\/IF and reacts with Mouse samples. Cited in 4 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPRZJU-21,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse,\u003cbr\u003e\nApplications:ICC\/IF, IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.,\u003cbr\u003e\nSpecificity:We have not been able to detect the endogenous mouse BTG4 with ab206914.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nBTG4 also known as B-cell translocation gene 4 is a protein with a molecular mass of approximately 26 kDa. This protein is part of the BTG\/Tob family which is involved in cell growth regulation. BTG4 is expressed predominantly in testicular tissue where it plays a role in germ cell development. Researchers also find it in lower amounts in other tissues such as the brain and ovary indicating a broader but less pronounced expression profile.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nBTG4 associates with several cellular processes including cell cycle regulation and transcriptional control. It does not operate as an isolated unit but forms complexes with elements like protein arginine methyltransferase suggesting functions in post-translational modifications. BTG4 influences mRNA deadenylation impacting mRNA stability and translation rates processes critical for cellular and developmental adjustments.\u003cbr\u003e\nPathways\u003cbr\u003e\nBTG4 plays a role in the cell cycle and mRNA degradation pathways. Its interaction with proteins like cyclin B1 and Cdc2 highlights its position in the regulation of cellular proliferation and division cycles. As part of these pathways BTG4 modulates key transitions in the cell cycle that ensure proper cellular functions and development.\u003cbr\u003e\nDisruption in BTG4 expression associates with infertility and certain cancers particularly testicular cancer. This relationship suggests BTG4's involvement in germ cell regulation failures. The association with proteins such as p53 in cancer pathways also illustrates its potential role in tumorigenesis through the influence on cell cycle checkpoints and apoptotic processes.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850332524713,"sku":"ab206914","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab206914","provider":"Iright","version":"1.0","type":"link"}