{"product_id":"abcam-ab211427","title":"Abcam, ab211427, Anti-RPS4X\/SCAR antibody","description":"\u003cp\u003eSize: 50µL\u003cbr\u003e\nRabbit Polyclonal RPS4X\/SCAR antibody. Suitable for IHC-P, WB, ICC\/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human RPS4X aa 50-150.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-P, ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human RPS4X aa 50-150. The exact immunogen used to generate this antibody is proprietary information.P62701\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRPS4X also known as SCAR is a ribosomal protein component of the small 40S subunit with a mass of approximately 29 kDa. Widely expressed RPS4X plays an important role in protein synthesis by contributing to ribosome assembly and function. Its presence is detected in various tissues which indicates its significant involvement in cellular protein production necessary for maintenance and survival.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nProteins that belong to the ribosomal protein family like RPS4X contribute to the formation of the ribosome structure. RPS4X participates in ribosomal assembly as part of the ribonucleoprotein complex. This role is critical for the synthesis of proteins shaping the cellular proteome and maintaining cellular functions. The ability of RPS4X to incorporate into the ribosome ensures that genetic information from mRNA is translated efficiently into the corresponding polypeptide chains.\u003cbr\u003e\nPathways\u003cbr\u003e\nProtein synthesis requires efficient coordination within the translation process where RPS4X functions. RPS4X is involved in the translation machinery alongside other ribosomal proteins and components like RPS6 and eIFs (eukaryotic initiation factors). These interactions are fundamental within the mRNA translation pathways and link RPS4X to processes such as the cell cycle and growth. Ribosomal proteins like RPS4X ensure proper translational control necessary for growth and development.\u003cbr\u003e\nProteins such as RPS4X have implications in ribosome-related dysfunctions. Its altered expression or mutation may associate with conditions like Diamond-Blackfan anemia a disorder characterized by defective erythrocyte production. Additionally anomalies in RPS4X are also linked to Turner syndrome where reduced ribosomal activity could play a contributing role. In both disorders there is a potential connection to ribosomal protein RPS19 which is also integral to ribosome function and pathology.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854157893801,"sku":"ab211427","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab211427","provider":"Iright","version":"1.0","type":"link"}