{"product_id":"abcam-ab222376","title":"Abcam, ab222376, YM-155, survivin inhibitor","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 443.3 Da, Purity \u0026gt;98%. Novel small molecule potent survivin suppressant. Inhibits survivin promoter activity (IC 50  = 0.54 nM) and down-regulates survivin  in vitro  and  in vivo.  Induces apoptosis in human tumor cell lines  in vitro  at 10 nM, with little effect on other IAP or Bcl-2 family members.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:781661-94-7,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:443.3 Da,\u003cbr\u003e\nMolecular formula:C20H19BrN4O3,\u003cbr\u003e\nPubChem:11178236,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 55 mM,\u003cbr\u003e\nBiochemical name:Sepantronium bromide,\u003cbr\u003e\nBiological description:Novel small molecule potent survivin suppressant. Inhibits survivin promoter activity (IC50 = 0.54 nM) and down-regulates survivin in vitro and in vivo. Induces apoptosis in human tumor cell lines in vitro at 10 nM, with little effect on other IAP or Bcl-2 family members.,\u003cbr\u003e\nCanonical smiles:CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-],\u003cbr\u003e\nInChi:InChI=1S\/C20H19N4O3.BrH\/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;\/h3-8,11H,9-10,12H2,1-2H3;1H\/q+1;\/p-1,\u003cbr\u003e\nInChiKey:QBIYUDDJPRGKNJ-UHFFFAOYSA-M,\u003cbr\u003e\nIUPAC Name:1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione;bromide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847501598889,"sku":"ab222376","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab222376","provider":"Iright","version":"1.0","type":"link"}