{"product_id":"abcam-ab227046","title":"Abcam, ab227046, Anti-galectin 9\/Gal-9 antibody [EPR22214]","description":"\u003cp\u003eSize: 20µL \/ 100µL \/ 1mL\u003cbr\u003e\nAnti-galectin 9\/Gal-9 antibody [EPR22214] (ab227046) is a rabbit monoclonal antibody detecting galectin 9\/Gal-9 in  Western Blot, Flow Cytometry (Intra), Flow Cytometry, IHC-P, ICC\/IF . Suitable for  Human . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR22214,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:ICC\/IF, IHC-P, WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.,\u003cbr\u003e\nSpecificity:This antibody is not recommended for mouse and rat in IHC.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nWhat is this antibody validated in?\u003cbr\u003e\nAnti-galectin 9\/Gal-9 antibody [EPR22214] (ab227046) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry\/immunofluorescence (ICC\/IF) in Human samples.\u003cbr\u003e\nWhat is the molecular weight of galectin 9\/Gal-9?\u003cbr\u003e\nAnti-galectin 9\/Gal-9 [EPR22214] (ab227046) specifically detects a band for galectin 9\/Gal-9 (UniProt: O00182) at a molecular weight of 40kDa.\u003cbr\u003e\nTrial sizes available!\u003cbr\u003e\nTest your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl.\u003cbr\u003e\nDiscover our selection of trial-size antibodies\u003cbr\u003e\nSpecificity confirmed\u003cbr\u003e\nThe specificity of Anti-galectin 9\/Gal-9 antibody [EPR22214] (ab227046) has been confirmed by Western blot testing in LGALS9 Knockout THP-1 cell line,\u003cbr\u003e\nab269505\u003cbr\u003e\nOther related products\u003cbr\u003e\nWe have a range of other formats of antibody clone [EPR22214] also available for your convenience: ab227046, Carrier free -\u003cbr\u003e\nab243288\u003cbr\u003e\n, Carrier free -\u003cbr\u003e\nab246797\u003cbr\u003e\n, PE -\u003cbr\u003e\nab306117\u003cbr\u003e\n, APC -\u003cbr\u003e\nab306118\u003cbr\u003e\n, HRP -\u003cbr\u003e\nab306119\u003cbr\u003e\n, Alkaline Phosphatase -\u003cbr\u003e\nab308677\u003cbr\u003e\n, Alexa Fluor® 488 -\u003cbr\u003e\nab309646\u003cbr\u003e\n, Alexa Fluor® 647 -\u003cbr\u003e\nab310012\u003cbr\u003e\n, Alexa Fluor® 594 -\u003cbr\u003e\nab310379\u003cbr\u003e\n, Alexa Fluor® 555 -\u003cbr\u003e\nab311904\u003cbr\u003e\n, Alexa Fluor® 568 -\u003cbr\u003e\nab312375\u003cbr\u003e\n, Alexa Fluor® 750 -\u003cbr\u003e\nab321429\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nGalectin-9 also known as Gal-9 or LGALS9 is a Β-galactoside-binding lectin with a molecular mass of around 40 kDa. It shows expression in various tissues including the thymus spleen and liver. The galectin-9 protein is involved in cell-cell and cell-matrix interactions where it binds to glycoproteins and glycolipids. Researchers commonly use methods like Galectin-9 ELISA to measure its levels in different biological samples.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nGalectins like galectin-9 play essential roles in regulating diverse immune responses. Galectin-9 acts within the immune system by modulating inflammation and apoptosis. It acts as both a pro-apoptotic factor for T cells and a protein mediator in innate immune functions. Galectin-9 proteins can form complexes with other lectins and cell surface receptors contributing to cellular signaling processes.\u003cbr\u003e\nPathways\u003cbr\u003e\nGalectin-9 is integral to the immune system's functional networks. It participates in the T-cell regulation pathways and the innate immunity pathways. In these pathways it interacts with other proteins like TIM-3 which mediates T-cell apoptosis and contributes to immune tolerance. These interaction networks play important roles in maintaining the body's immune homeostasis.\u003cbr\u003e\nGalectin-9 has associations with autoimmune diseases and cancer. Its regulatory effects on T cells connect it to autoimmune conditions where abnormal T-cell activation occurs. In cancer the alteration in galectin-9 expression levels affects tumor immunity. The interaction of galectin-9 with other proteins like TIM-3 is important in cancer progression making it a target of interest for therapeutic interventions.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850283274409,"sku":"ab227046","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab227046","provider":"Iright","version":"1.0","type":"link"}