{"product_id":"abcam-ab232644","title":"Abcam, ab232644, Anti-ATP synthase C antibody [EPR13907] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal ATP synthase C antibody. Carrier free. Suitable for WB, ICC\/IF and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR13907,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab232644 is the carrier-free version of\u003cbr\u003e\nab181243\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nATP synthase subunit c also known as ATP synthase C ATP-C or ATP synthase C subunit is an integral component of the ATP synthase complex. This protein has a known molecular mass of approximately 8.3 kDa. It is prominently expressed in mitochondrial membranes where it serves as an important part of the proton channel. Its primary function involves facilitating the conversion of proton motive force into rotational mechanical energy which drives ATP synthesis. Through this mechanical action ATP synthase C contributes significantly to energy conversion within cells.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nATP synthase C functions as a critical component of the ATP synthase enzyme complex also known as FoF1 ATPase or Complex V of the oxidative phosphorylation pathway. This subunit forms a ring structure that allows protons to move across the mitochondrial membrane which is necessary for the synthesis of ATP from ADP and inorganic phosphate. By participating in this synthesis process ATP synthase C impacts cellular energy metabolism affecting various physiological functions dependent on ATP as an energy source.\u003cbr\u003e\nPathways\u003cbr\u003e\nATP synthase C plays an essential role within the oxidative phosphorylation pathway. This pathway is integral to cellular respiration and is responsible for the majority of ATP production in aerobic organisms. ATP synthase C interacts with other proteins such as the ATP synthase alpha and beta subunits which form the catalytic core of the enzyme. These interactions are central to the energy currency of the cell ensuring efficient energy conversion and transfer.\u003cbr\u003e\nATP synthase C is implicated in mitochondrial dysfunctions and associated conditions such as mitochondrial myopathies and neurodegenerative diseases. Mitochondrial myopathies result from defects in the oxidative phosphorylation pathway often involving proteins like cytochrome c oxidase which are important for efficient ATP production. Disorders related to ATP synthase C dysfunction can cause significant impacts on tissues that require high energy reflecting its critical role in maintaining cellular energy balance.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851860234409,"sku":"ab232644","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab232644","provider":"Iright","version":"1.0","type":"link"}