{"product_id":"abcam-ab237533","title":"Abcam, ab237533, Anti-TMEM161A antibody","description":"\u003cp\u003eSize: 100µL\u003cbr\u003e\nRabbit Polyclonal TMEM161A antibody. Suitable for WB, IHC-P, ICC\/IF and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM161A aa 1-100.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Rat, Human,\u003cbr\u003e\nApplications:WB, ICC\/IF, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human TMEM161A aa 1-100. The exact immunogen used to generate this antibody is proprietary information.Q9NX61\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein G, Purification notes-Purity greater than 95%, Storage buffer-pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nTMEM161A also known as Transmembrane Protein 161A is a member of the larger transmembrane protein family. Structurally TMEM161A is characterized by multiple transmembrane domains. Its mass is approximately 55 kDa. Researchers have observed its expression in various tissues including the brain and kidney. The exact mechanical role is not fully elucidated but it is suggested to play a role in cellular communication through its membrane localization.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nTMEM161A contributes to cellular processes involving intercellular signaling and ion transport. Although scientists have not yet identified a specific complex that includes TMEM161A its function as a transmembrane protein implies potential involvement in forming channels or receptors. These elements are important for maintaining ionic balances and signaling pathways inside cells indicating TMEM161A as a supportive component in these processes.\u003cbr\u003e\nPathways\u003cbr\u003e\nRecent findings indicate TMEM161A's potential involvement in cell signaling and transport pathways. An important pathway that features TMEM161A activity includes signal transduction where it may interact with proteins like ion channels such as voltage-gated channels. These interactions suggest TMEM161A could modulate responses to cellular environment changes linking it to broader cellular response mechanisms.\u003cbr\u003e\nScientists have noted potential links between TMEM161A and neurological disorders. Some studies suggest its involvement in conditions like epilepsy where abnormal ion transport plays a significant role. Alterations in TMEM161A expression might impact channel proteins such as voltage gated potassium channels which are important for maintaining action potentials in neurons potentially exacerbating these conditions. Research continues to explore TMEM161A's full role in these disorders.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854115983529,"sku":"ab237533","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab237533","provider":"Iright","version":"1.0","type":"link"}