{"product_id":"abcam-ab249641","title":"Abcam, ab249641, Anti-DHRSX antibody [EPR7753(2)] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal DHRSX antibody. Carrier free. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR7753(2),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:Flow Cyt (Intra), WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab249641 is the carrier-free version of\u003cbr\u003e\nab171736\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nDHRSX (Dehydrogenase\/Reductase (SDR Family) Member X) is a protein of interest in various biological studies. It is known for its role in oxidoreductase activity and commonly does not have other alternate names. The protein mass is approximately 37 kDa. DHRSX expresses in multiple tissues with notable expression in the brain and liver suggesting a diverse role across different systems.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe protein DHRSX affects cellular processes by participating in metabolism. It does not seem to be a part of a larger protein complex indicating its function may rely more on individual activity. Its capability to act in reduction-oxidation reactions helps cells manage oxidative stress and maintain metabolic balance. The effects of DHRSX have implications in normal cellular function and development.\u003cbr\u003e\nPathways\u003cbr\u003e\nDHRSX is important in the metabolic and detoxification pathways. It engages with the NADP\/NADPH cofactor system influencing the oxidative status of cells and supporting cellular defense against reactive oxygen species. Additionally the interaction with proteins like ADH1 (Alcohol Dehydrogenase 1) further integrates DHRSX into enzymatic pathways critical for metabolizing alcohols and aldehydes.\u003cbr\u003e\nDHRSX has potential links to metabolic syndromes and liver disease. Research has found that irregular DHRSX expression correlates with metabolic disorders like obesity possibly through disruption in glucose and lipid metabolism. The protein's activity appears connected to other metabolic proteins such as PPARα (Peroxisome Proliferator-Activated Receptor Alpha) shedding light on how disturbances in DHRSX can contribute to broader metabolic issues.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851883991209,"sku":"ab249641","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab249641","provider":"Iright","version":"1.0","type":"link"}