{"product_id":"abcam-ab251097","title":"Abcam, ab251097, Anti-SLP-2 antibody [EPR18718] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal SLP-2 antibody. Carrier free. Suitable for ICC\/IF, IP, WB, Flow Cyt (Intra) and reacts with Human, Mouse, Rat samples. Cited in 2 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR18718,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:Flow Cyt (Intra), IP, ICC\/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab251097 is the carrier-free version of\u003cbr\u003e\nab191883\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nSLP-2 also known as stomatin-like protein 2 is a protein with a mass of approximately 38 kDa. It is widely expressed in different tissues with high presence in mitochondrial inner membrane domains. This protein belongs to the stomatin protein family and possesses functions related to cellular compartmentalization and stability.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nStomatin-like protein 2 is integral to maintaining mitochondrial morphology and function. It is closely involved in regulating mitochondrial membrane potential and apoptosis. As part of a multiprotein complex SLP-2 helps in organizing lipid and protein microdomains which are important for various mitochondrial processes and cellular energy dynamics.\u003cbr\u003e\nPathways\u003cbr\u003e\nStomatin-like protein 2 contributes significantly to the oxidative phosphorylation and apoptosis pathways. It interacts with proteins such as prohibitins which are critical in maintaining mitochondria integrity and function. These interactions highlight SLP-2's role in both energy production and programmed cell death highlighting its significance in cellular metabolic regulation and stress response.\u003cbr\u003e\nStomatin-like protein 2 has been linked to cancer and cardiovascular disorders. Its up-regulation is often observed in various cancers suggesting a role in tumorigenesis by affecting the cellular energy balance and mitochondrial dynamics. The protein also connects to cardiolipin a lipid implicated in heart diseases illustrating its involvement in cardiovascular conditions through mitochondrial dysfunction.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851628695721,"sku":"ab251097","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab251097","provider":"Iright","version":"1.0","type":"link"}