{"product_id":"abcam-ab251198","title":"Abcam, ab251198, Anti-Arginine (glcnac ) antibody [EPR18251] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal Arginine antibody. Carrier free. Suitable for WB and reacts with Modified Amino Acid samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR18251,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab251198 is the carrier-free version of\u003cbr\u003e\nab195033\u003cbr\u003e\nThis antibody was developed as part of a collaboration between Abcam and the lab of Dr. Feng Shao, National Institute of Biological Sciences (NIBS), Beijing.\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nArginine often referred to as ARG plays a central role in various biological processes. It is an amino acid with a molecular weight of about 174.2 Da. Arginine is expressed in multiple tissues including the liver and endothelium. It often serves as a precursor for the synthesis of various biomolecules such as nitric oxide. In scientific literature you may also encounter it under alternative spellings like 'arganine' or 'argenine' though these are less common.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nArginine contributes to protein synthesis and serves as a substrate for enzymes like nitric oxide synthase. It forms part of larger protein complexes and participates in metabolic pathways. Nitric oxide produced from arginine acts as a signaling molecule that modulates vascular function by inducing vasodilation. It also takes part in immune responses and has a role in cell division wound healing and hormone release.\u003cbr\u003e\nPathways\u003cbr\u003e\nArginine plays a significant role in the urea cycle and the nitric oxide signaling pathway. It interacts with proteins such as ornithine transcarbamylase in the urea cycle facilitating the removal of ammonia. Meanwhile in the nitric oxide pathway it collaborates with nitric oxide synthase to produce nitric oxide which affects smooth muscle relaxation and neurotransmission.\u003cbr\u003e\nArginine has connections to cardiovascular diseases and immune-associated conditions. The production of nitric oxide which involves arginine impacts cardiovascular health and its dysregulation can lead to hypertension. Additionally arginine metabolism influences conditions like arginase deficiency which affects the urea cycle. These conditions can involve other proteins such as ornithine transcarbamylase demonstrating the interlinked nature of arginine with various biological and pathological processes.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851570204841,"sku":"ab251198","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab251198","provider":"Iright","version":"1.0","type":"link"}