{"product_id":"abcam-ab269700","title":"Abcam, ab269700, Galanthamine, cholinesterase inhibitor","description":"\u003cp\u003eSize: 100mg \/ 500mg\u003cbr\u003e\nMW 287.35 Da. Potent selective acetylcholinesterase inhibitor (IC 50  = 410 nM). Greater than 50-fold selective versus butyrylcholinesterase. Inhibits RBC cholinesterase activity 10-fold more potently than that of human brain tissue. Reduces apoptotic effect of thapsigargin in SH-SY5Y cells. Non-competitive nicotinic receptor aganist in rat PC12 cells. Neuroprotective following ischemia-reperfusion injury in animal models.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:357-70-0,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:287.35 Da,\u003cbr\u003e\nMolecular formula:C17H21NO3,\u003cbr\u003e\nPubChem:9651,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 50 mMSoluble in ethanol to 100 mM with gentle warming,\u003cbr\u003e\nBiochemical name:Galantamine,\u003cbr\u003e\nBiological description:Potent selective acetylcholinesterase inhibitor (IC50 = 410 nM). Greater than 50-fold selective versus butyrylcholinesterase. Inhibits RBC cholinesterase activity 10-fold more potently than that of human brain tissue. Reduces apoptotic effect of thapsigargin in SH-SY5Y cells. Non-competitive nicotinic receptor aganist in rat PC12 cells. Neuroprotective following ischemia-reperfusion injury in animal models.,\u003cbr\u003e\nCanonical smiles:CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O,\u003cbr\u003e\nIsomeric smiles:CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O,\u003cbr\u003e\nInChi:InChI=1S\/C17H21NO3\/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17\/h3-6,12,14,19H,7-10H2,1-2H3\/t12-,14-,17-\/m0\/s1,\u003cbr\u003e\nInChiKey:ASUTZQLVASHGKV-JDFRZJQESA-N,\u003cbr\u003e\nIUPAC Name:(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847480103081,"sku":"ab269700","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab269700","provider":"Iright","version":"1.0","type":"link"}