{"product_id":"abcam-ab285435","title":"Abcam, ab285435, BMS-986158","description":"\u003cp\u003eSize: 1mg \/ 5mg\u003cbr\u003e\nMW 495.6 Da, Purity \u0026gt;98%. BMS-986158 is a potent bromodomain (BRD) and extra-terminal domain (BET) family inhibitor. BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1800340-40-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:495.6 Da,\u003cbr\u003e\nMolecular formula:C30H33N5O2,\u003cbr\u003e\nPubChem:118196485,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:DMSO,\u003cbr\u003e\nBiochemical name:Bms-986158,\u003cbr\u003e\nBiological description:BMS-986158 is a potent bromodomain (BRD) and extra-terminal domain (BET) family inhibitor. BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.,\u003cbr\u003e\nCanonical smiles:CC1=C(N(N=N1)C)C2=CC3=C(C4=C(N3C(C5CCOCC5)C6=CC=CC=C6)C=C(C=C4)C(C)(C)O)N=C2,\u003cbr\u003e\nIsomeric smiles:CC1=C(N(N=N1)C)C2=CC3=C(C4=C(N3[C@@H](C5CCOCC5)C6=CC=CC=C6)C=C(C=C4)C(C)(C)O)N=C2,\u003cbr\u003e\nInChi:InChI=1S\/C30H33N5O2\/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21\/h5-11,16-18,21,29,36H,12-15H2,1-4H3\/t29-\/m1\/s1,\u003cbr\u003e\nInChiKey:KGERZPVQIRYWRK-GDLZYMKVSA-N,\u003cbr\u003e\nIUPAC Name:2-[3-(3,5-dimethyltriazol-4-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]pyrido[3,2-b]indol-7-yl]propan-2-ol\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2021 BMS-986158. B2021-5 is the same size as the 5 mg size of ab285435.\u003cbr\u003e\nProtect from air and light.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847500353705,"sku":"ab285435","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab285435","provider":"Iright","version":"1.0","type":"link"}