{"product_id":"abcam-ab286964","title":"Abcam, ab286964, PF-9366","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 350.8 Da, Purity \u0026gt;98%. An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform (IC 50  = 420 nM). PF-9366 inhibits cellular S-Adenosyl-L-methionine (SAM) production with an IC 50  of 1.2 μM in H520 lung carcinoma cells.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:72882-78-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:350.8 Da,\u003cbr\u003e\nMolecular formula:C20H19ClN4,\u003cbr\u003e\nPubChem:12612431,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO,\u003cbr\u003e\nBiochemical name:PF 9366-Bio-X,\u003cbr\u003e\nBiological description:An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform (IC50 = 420 nM). PF-9366 inhibits cellular S-Adenosyl-L-methionine (SAM) production with an IC50 of 1.2 μM in H520 lung carcinoma cells.,\u003cbr\u003e\nCanonical smiles:CN(C)CCC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=C2)C4=CC=CC=C4,\u003cbr\u003e\nInChi:InChI=1S\/C20H19ClN4\/c1-24(2)11-10-19-22-23-20-13-16(14-6-4-3-5-7-14)17-12-15(21)8-9-18(17)25(19)20\/h3-9,12-13H,10-11H2,1-2H3,\u003cbr\u003e\nInChiKey:LYLASWLQCMKZAT-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-(7-chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethanamine\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2244 PF-9366. B2244-5 is the same size as the 5 mg size of ab286964.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847499305129,"sku":"ab286964","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab286964","provider":"Iright","version":"1.0","type":"link"}