{"product_id":"abcam-ab287030","title":"Abcam, ab287030, Netarsudil dihydrochloride (AR-13324)","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 526.4 Da, Purity \u0026gt;98%. Netarsudil Hydrochloride (AR-13324) is a Rho kinase (ROCK) inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous humor. Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2; a novel ocular hypotensive agent for the treatment of glaucoma.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1253952-02-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:526.4 Da,\u003cbr\u003e\nMolecular formula:C28H29Cl2N3O3,\u003cbr\u003e\nPubChem:66599892,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to \u0026gt;25 mM,\u003cbr\u003e\nBiochemical name:Netarsudil dihydrochloride,\u003cbr\u003e\nBiological description:Netarsudil Hydrochloride (AR-13324) is a Rho kinase (ROCK) inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous humor. Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2; a novel ocular hypotensive agent for the treatment of glaucoma.,\u003cbr\u003e\nCanonical smiles:CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)C(CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl,\u003cbr\u003e\nIsomeric smiles:CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C28H27N3O3.2ClH\/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;;\/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H\/t26-;;\/m1..\/s1,\u003cbr\u003e\nInChiKey:LDKTYVXXYUJVJM-FBHGDYMESA-N,\u003cbr\u003e\nIUPAC Name:[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate;dihydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2387 Netarsudil dihydrochloride. B2387-5 is the same size as the 5 mg size of ab287030.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847498125481,"sku":"ab287030","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab287030","provider":"Iright","version":"1.0","type":"link"}