{"product_id":"abcam-ab287043","title":"Abcam, ab287043, CC-90003","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 458.4 Da, Purity \u0026gt;98%. CC-90003 is a potent extracellular signal-regulated kinases (ERK1\/2) inhibitor. CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)\/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1621999-82-3,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:458.4 Da,\u003cbr\u003e\nMolecular formula:C22H21F3N6O2,\u003cbr\u003e\nPubChem:90331177,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to \u0026gt;100 mM,\u003cbr\u003e\nBiochemical name:CID 90331177,\u003cbr\u003e\nBiological description:CC-90003 is a potent extracellular signal-regulated kinases (ERK1\/2) inhibitor. CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)\/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.,\u003cbr\u003e\nCanonical smiles:CC1=CC(=C(C=C1)NC2=NC(=NC=C2C(F)(F)F)NC3=CC(=NC=C3C)OC)NC(=O)C=C,\u003cbr\u003e\nInChi:InChI=1S\/C22H21F3N6O2\/c1-5-18(32)28-17-8-12(2)6-7-15(17)29-20-14(22(23,24)25)11-27-21(31-20)30-16-9-19(33-4)26-10-13(16)3\/h5-11H,1H2,2-4H3,(H,28,32)(H2,26,27,29,30,31),\u003cbr\u003e\nInChiKey:ILUKRINUNLAVMH-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:N-[2-[[2-[(2-methoxy-5-methylpyridin-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2419 CC-90003. B2419-5 is the same size as the 5 mg size of ab287043.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847498027177,"sku":"ab287043","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab287043","provider":"Iright","version":"1.0","type":"link"}