{"product_id":"abcam-ab309454","title":"Abcam, ab309454, Human CTRP4 ELISA Kit","description":"\u003cp\u003eSize: 1 x 96Tests\u003cbr\u003e\nHuman CTRP4 ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human CTRP4 in Human in Biofluids, Cell Culture Media samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nDetection method:Colorimetric,\u003cbr\u003e\nSample types:Serum, Plasma, Cell culture supernatant,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nAssay type:Sandwich (quantitative),\u003cbr\u003e\nSensitivity:= 0.14 ng\/mL,\u003cbr\u003e\nRange:0.14 - 40 ng\/mL,\u003cbr\u003e\nAssay Platform:Pre-coated microplate (12 x 8 well strips)\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nHuman CTRP4 ELISA Kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CTRP4 in serum, plasma, and cell culture supernatants. This assay employs an antibody specific for Human CTRP4 coated on a 96-well plate.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information--20°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nCTRP4 also known as C1q and tumor necrosis factor-related protein 4 is a member of the C1q\/TNF-related protein family. It has a molecular weight of approximately 31 kDa. The protein is expressed in various tissues including adipose tissue and the liver where it performs regulatory functions by interacting with other cellular components. Its presence in these tissues suggests roles in metabolism and inflammation.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nCTRP4 functions as a modulator of immune responses and energy balance. It is involved in forming complexes that can influence inflammatory pathways playing a part in controlling cytokine production. As a member of the CTRP family CTRP4 shares structural homology that allows it to interact with receptors implicated in metabolic and immune processes. This connection points to its role in maintaining homeostasis.\u003cbr\u003e\nPathways\u003cbr\u003e\nCTRP4 participates in metabolic and inflammatory signaling networks. It engages in the AMPK signaling pathway which is critical for energy regulation. Within this context CTRP4 acts together with proteins like adiponectin to modulate glucose uptake and lipid metabolism. In the inflammatory landscape CTRP4 influences the MAPK signaling pathway affecting cellular responses to various stressors and regulatory signals.\u003cbr\u003e\nCTRP4 has associations with obesity and type 2 diabetes. Its role in these conditions links to its function in metabolic regulation and inflammation control. For instance CTRP4 modulates inflammatory profiles connecting it with proteins such as TNF-alpha in the context of metabolic syndrome. Research continues to explore its potential as a therapeutic target given its involvement in these significant health challenges.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843784659113,"sku":"ab309454","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab309454","provider":"Iright","version":"1.0","type":"link"}