{"product_id":"abcam-ab96286","title":"Abcam, ab96286, Anti-OSBPL6 antibody","description":"\u003cp\u003eSize: 50µL\u003cbr\u003e\nRabbit Polyclonal OSBPL6 antibody. Suitable for WB, IHC-P, ICC\/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human OSBPL6 aa 850 to C-terminus.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:ICC\/IF, WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human OSBPL6 aa 850 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q9BZF3\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.01% Thimerosal (merthiolate)Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe protein OSBPL6 also known as ORP6 belongs to the oxysterol-binding protein (OSBP) family. It weighs approximately 99 kDa. OSBPL6 is ubiquitously expressed in various tissues with noticeable levels found in the brain and liver. Mechanically OSBPL6 plays a role in lipid binding and transport. Through its mechanism it regulates lipid homeostasis and may function in intracellular lipid dynamics.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nOSBPL6 impacts lipid metabolism and cellular signaling. It associates with membranes and may form part of a larger protein complex involved in lipid transfer between organelles. This activity impacts the way cells handle lipids and contributes to maintaining lipid balance within the cell. The identification of OSBPL6 in various cell types indicates its broad involvement in cellular activities related to lipids.\u003cbr\u003e\nPathways\u003cbr\u003e\nOSBPL6 engages in lipid metabolism and regulation pathways. It is notably linked with cholesterol homeostasis and phosphoinositide signaling. OSBPL6 interacts with other members of the OSBP family potentially facilitating collaboration or competition among these proteins. These interactions highlight its significance in regulating cellular lipid environments and influencing related biological pathways.\u003cbr\u003e\nOSBPL6's involvement shines in metabolic and neurodegenerative conditions. Altered expression or dysfunction of OSBPL6 may contribute to cholesterol-related disorders such as atherosclerosis. Furthermore disruptions in lipid regulation connected to OSBPL6 could have implications for conditions like Alzheimer's disease. In these diseases OSBPL6 might interact with proteins involved in lipid metabolism and signaling adding complexity to its role in disease contexts.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854126403753,"sku":"ab96286","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab96286","provider":"Iright","version":"1.0","type":"link"}