{"product_id":"biolegend-127406","title":"Biolegend, 127406, Alexa Fluor® 488 anti-mouse Podoplanin Antibody, 100μg","description":"\u003cp\u003eThe mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Syrian Hamster\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunohistochemistry6, and spatial biology (IBEX)8,9.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Farr A, et al. 1992. J. Histochem. Cytochem. 40:651. Farr AG, et al. 1992. J. Exp. Med. 176:1477. Bekiaris V, et al. 2008. J. Immunol. 180:6768. Algars A, et al. 2011. Blood 117:4387. PubMed Reis VO, et al. 2012. Immunobiology. 217:831. PubMed Kaji C, et al. 2012. Acta. Histochem. Cytochem. 45:227. (IHC) Kretschmer S, et al. 2013. PLoS One. 8:e52201. PubMed. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed\u003cbr\u003e\nProduct Citations: Naito H, et al. 2020. Nature Protocols. 15(3):1066-1081. PubMed Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed Du Y, et al. 2022. FASEB J. 36:e22248. PubMed Hoorweg K, et al. 2015. J Immunol. 195: 4257 - 4263. PubMed Rodda LB et al. 2018. Immunity. 48(5):1014-1028 . PubMed Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed Sokol CL et al. 2018. Immunity. 49(3):449-463 . PubMed Jackson-Jones LH, et al. 2020. Immunity. 52:700. PubMed Nadafi R, et al. 2020. Cell Reports. 30(12):4110-4123. PubMed Jung M, et al. 2016. Sci Signal. 9: ra64. PubMed Durré T, et al. 2018. Nat Commun. 9:5178. PubMed\u003cbr\u003e\nRRID: AB_1133992 (BioLegend Cat. No. 127405) AB_2161930 (BioLegend Cat. No. 127406)\u003cbr\u003e\nStructure: 43 Kd glycosylated type-1 transmembrane protein. Mucin-type protein.\u003cbr\u003e\nDistribution: Expressed on epithelial and mesothelial cells.\u003cbr\u003e\nCell Type: Epithelial cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nAntigen References: 1. Farr A, et al. 1992. J. Histochem. Cytochem. 40:651. 2. Schacht V, et al. 2005. Am. J. Pathol. 166:913.\u003cbr\u003e\nGene ID: 14726\u003cbr\u003e\nUniProt: View information about Podoplanin on UniProt.org\u003cbr\u003e\nClone: 8.1.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T1a, gp38, stromal cell marker\u003cbr\u003e\nIsotype: Syrian Hamster IgG\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862491025577,"sku":"127406","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-127406","provider":"Iright","version":"1.0","type":"link"}