{"product_id":"biolegend-127705","title":"Biolegend, 127705, FITC anti-mouse TCR Vα8.3 Antibody, 50μg","description":"\u003cp\u003eThe B21.14 antibody recognizes an epitope of the CDR1 on the Va 8.3 subfamily of TCR having the a,b,c and d haplotypes of Tcra gene complex.\u003cbr\u003e\n50μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Soluble TCR from mouse CTL clone CW3\/1.1\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Necker A, et al. 1991. Eur J. Immunol. 21:3035 Brodnicki TC, et al. 1996. Mol Immunol 33:253 Tomonari K, et al. 1992. Immunogenetics 35:291\u003cbr\u003e\nRRID: AB_1186078 (BioLegend Cat. No. 127705)\u003cbr\u003e\nStructure: TCR has a two chain structure, consisting of alpha and beta chain. It belongs to Ig superfamily.\u003cbr\u003e\nDistribution: On a subset of T cells\u003cbr\u003e\nFunction: Recognize MHC\/peptide complex on the antigen-presenting cells.\u003cbr\u003e\nInteraction: Associate with CD3 complex to form TCR complexes expressing on cell surface.\u003cbr\u003e\nLigand\/Receptor: TCR recognizes MHC\/peptide complex\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Kubo RT, et al. 1989. J. Immunol. 142:2736 2. Brodnicki TC, et al. 1996. Mol Immunol 33:253\u003cbr\u003e\nGene ID: 110469\u003cbr\u003e\nUniProt: View information about TCR Valpha8.3 on UniProt.org\u003cbr\u003e\nClone: B21.14\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor Vα 8.3\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862549844137,"sku":"127705","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-127705","provider":"Iright","version":"1.0","type":"link"}