{"product_id":"biolegend-133302","title":"Biolegend, 133302, FITC anti-mouse Lineage Cocktail with Isotype Ctrl, 100tests","description":"\u003cp\u003eThe mouse lineage panel has been designed to react with cells from the major hematopoietic cell lineages, such as T lymphocytes, B lymphocytes, monocytes\/macrophages, granulocytes, NK cells, and erythrocytes. The FITC Mouse Lineage Antibody Cocktail is designed for the flow cytometric identification of hematopoietic progenitors in mouse bone marrow. Components include anti-mouse CD3ε, clone 145-2C11; anti-mouse Ly-6G\/Ly-6C, clone RB6-8C5; anti-mouse CD11b, clone M1\/70; anti-mouse CD45R\/B220, clone RA3-6B2; anti-mouse TER-119\/Erythroid cells, clone Ter-119. FITC Mouse Lineage Isotype Control Cocktail contains equivalent concentrations of isotype-matched negative control immunoglobulin.   Materials provided: 1. FITC anti-mCD3ε\/ FITC anti-mGr-1\/ FITC anti-mCD11b\/ FITC anti-mCD45R(B220)\/ FITC anti-mTer-119, 25 tests 2. FITC Armenian hamster IgG\/ FITC Rat IgG2b\/ FITC Rat IgG2a isotype controls, 25 tests  Materials not provided: Cell Staining Buffer (Cat. No. 420201)\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nFormulation: This two-reagent set contains FITC conjugated antibodies and isotype controls in optimal concentration for flow cytometric analysis.\u003cbr\u003e\nPreparation: The antibodies are purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solutions should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of these antibodies is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Morris SJ, et al. 1997. Development. 124(10):1929-1939 Okada S, et al. 1992. Blood180 (12):3044-3050 Spangrude GJ, et al. 1988. Science 241 (4861):58-62 Spangrude GJ, et al. 1990. Exp Hematol. 18 (8):920-926 Tan SL, et al. 2006. J. Immunol. 176:2872. PubMed Ito R, et al. 2012. Exp Hematol. 40:953. PubMed.\u003cbr\u003e\nProduct Citations: Sakae H, et al. 2023. Cells. 12:. PubMed Guan H, et al. 2023. Int J Mol Sci. 24:. PubMed Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed Tikka C, et al. 2023. Front Immunol. 14:1026368. PubMed Feng X, et al. 2023. Nat Commun. 14:3208. PubMed Zhang S, et al. 2022. Mol Carcinog. 61:408. PubMed Cao Y, et al. 2023. J Inflamm Res. 16:343. PubMed Dean BD, et al. 2023. J Immunother Cancer. 11: . PubMed Broxmeyer HE, et al. 2021. Blood Cells Mol Dis. 86:102492. PubMed Broxmeyer HE, et al. 2022. Stem Cell Rev Rep. 18:2513. PubMed Li X, et al. 2022. Cell. 185:1709. PubMed Cai Q, et al. 2018. Blood Cells Mol Dis. 71:23. PubMed Chen G, et al. 2014. Cancer Immunol Res. 2:949. PubMed Xue Y et al. 2017. Developmental cell. 42(4):349-362 . PubMed Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed Capitano ML, et al. 2020. Blood Cells Mol Dis. 102435:84. PubMed Liu J, et al. 2017. Am J Pathol. 10.1016\/j.ajpath.2017.02.010. PubMed Gao S, et al. 2022. Cell Res. 32:38. PubMed Calcinotto A, et al. 2018. Nat Commun. 9:4832. PubMed Zhang Y, et al. 2021. J Immunol Res. 2021:5599439. PubMed Wang X, et al. 2018. Cell Death Dis. 9:578. PubMed Oka Y, et al. 2020. Sci Adv. 6:. PubMed Capitano ML, et al. 2019. J Clin Invest. 130:2555. PubMed Ganguly S, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:891. PubMed Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed Yu Q, et al. 2016. Cell Res. 10.1038\/cr.2016.85. PubMed Hoffmann J, et al. 2021. Nat Commun. 12:3964. PubMed Fujimoto M, et al. 2022. Nat Commun. 13:5408. PubMed Capitano ML, et al. 2021. J Clin Invest. 131:. PubMed Astuti Y, et al. 2017. Stem Cell Reports. 8(1):177-190. PubMed Liu X, et al. 2015. Nat Commun. 6: 8825. PubMed\u003cbr\u003e\nRRID: AB_10697030 (BioLegend Cat. No. 133301) AB_10697030 (BioLegend Cat. No. 133302)\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nGene ID: 104231\u003cbr\u003e\nUniProt: View information about Lineage on UniProt.org\u003cbr\u003e\nClone: 145-2C11; RB6-8C5; RA3-6B2; Ter-119; M1\/70;\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Lin-1\u003cbr\u003e\nIsotype: Armenian Hamster IgG\/Rat IgG2a\/Rat IgG2b\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860805669033,"sku":"133302","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-133302","provider":"Iright","version":"1.0","type":"link"}