{"product_id":"biolegend-137402","title":"Biolegend, 137402, Purified anti-mouse Ly49G Antibody, 500μg","description":"\u003cp\u003eLy49G is a type II transmembrane protein belonging to the family of Ly49 proteins, each having specificity for a small repertoire of MHC I alleles that are generally recognized in a peptide-independent manner.   The Ly49 family of MHC class I receptors shows a high degree of variability between mouse strains.  It is expressed on a subset of NK cells and some NKT cell lines.  The AT8 antibody reacts with the Ly49G receptor from BALB\/c, 129\/J, 129Sv\/J, SJL, FVB\/N, A\/J, C3H\/HeJ, C3H\/HeNCr, CBA\/J, and CBA\/NCr mice.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: IL-2-activated 129\/J NK cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Makrigiannis AP, et al. 2004. J. Immunol. 172:1414.\u003cbr\u003e\nRRID: AB_10551620 (BioLegend Cat. No. 137402)\u003cbr\u003e\nStructure: A type II transmembrane protein belonging to Ly49 family.\u003cbr\u003e\nDistribution: Subset of NK cells and some NKT cell lines\u003cbr\u003e\nFunction: Allele-specific MHC recognition\u003cbr\u003e\nLigand\/Receptor: MHC class I molecules\u003cbr\u003e\nCell Type: NK cells, NKT cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: MHC Antigens\u003cbr\u003e\nAntigen References: Lavender KJ, et al. 2006. J. Immunol. 177:8578. Pascal V, et al. 2007. J. Immunol.. 179:1751. Lavender KJ, et al. 2007. J. Immunol. 179:6856. Rouhi A, et al. 2007. Mol. Immunol. 44(5):821.\u003cbr\u003e\nGene ID: 16638\u003cbr\u003e\nUniProt: View information about Ly49G on UniProt.org\u003cbr\u003e\nClone: AT8\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ly-49G, Ly49g, Killer cell lectin-like receptor 7, Klra7\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862543782057,"sku":"137402","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-137402","provider":"Iright","version":"1.0","type":"link"}