{"product_id":"biolegend-139803","title":"Biolegend, 139803, PE anti-mouse TCR Vβ9 Antibody, 25μg","description":"\u003cp\u003eVβ9 T cell receptor (TCR Vβ9) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α\/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate T cell-mediated immune responses. Murine Vβ9 cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens.Mice bearing a and c haplotypes have Vβ9 gene deletion.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Mouse T-cell hybridoma 2BR18\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Utsunomiya Y, et al. 1991. Eur. J. Immunol. 21:1007. (FC)\u003cbr\u003e\nProduct Citations: Prendergast ÁM, et al. 2017. Haematologica. 445:102. PubMed Caeser R, et al. 2019. Nat Commun. 4543:10. PubMed Nelson CE et al. 2019. Cell Rep. 28(12):3092-3104 . PubMed\u003cbr\u003e\nRRID: AB_10640824 (BioLegend Cat. No. 139803) AB_10641563 (BioLegend Cat. No. 139804)\u003cbr\u003e\nStructure: Member of the immunoglobulin superfamily, Vβ9 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer.\u003cbr\u003e\nDistribution: Subset of TCR αβ+ T cells\u003cbr\u003e\nFunction: Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.\u003cbr\u003e\nLigand\/Receptor: MHC-peptide complex\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Ortman RA, et al. 1994. J. Immunol. 152:4175. 2. Niimi N, et al. 1994. Immunogenetics 40:312. 3. Pied s, et al. 1997. Int. Immunol. 9:17.\u003cbr\u003e\nGene ID: 21577\u003cbr\u003e\nUniProt: View information about TCR Vbeta9 on UniProt.org\u003cbr\u003e\nClone: MR10-2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Vβ9 T-cell receptor, T cell receptor beta 9\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866153078953,"sku":"139803","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-139803","provider":"Iright","version":"1.0","type":"link"}