{"product_id":"biolegend-152402","title":"Biolegend, 152402, Purified anti-mouse CD19 Antibody, 500μg","description":"\u003cp\u003eCD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Transfected k562 cells expressing the extracellular domain of murine CD19.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested Block, IP - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP) Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)\u003cbr\u003e\nProduct Citations: Wolf Y, et al. 2017. J Exp Med. 214:905. PubMed Paterson MJ, et al. 2020. PLoS Pathog. 16:e1008733. PubMed Burrello C, et al. 2018. Front Med (Lausanne). 5:21. PubMed Lei Y, et al. 2022. Comp Med. 72:93. PubMed Cao Q, et al. 2018. Am J Physiol Renal Physiol. 314:F561. PubMed Dienz O, et al. 2020. J Immunol. 204:1521. PubMed Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed Dooley K, et al. 2021. Mol Ther. 29:1729. PubMed King IL, et al. 2017. Mucosal Immunol. 10:1160. PubMed Ye Y, et al. 2017. Sci Immunol. 2:17. PubMed Yoon BH, et al. 2018. Mol Cells. 41:953. PubMed Li J, et al. 2021. Front Immunol. 12:710406. PubMed Rosenbaum M, et al. 2019. Nat Commun. 2.05. PubMed Rive CM, et al. 2022. Mol Ther Methods Clin Dev. 26:4. PubMed Duncan CG, et al. 2018. G3 (Bethesda). 0.892361111. PubMed Liu J, et al. 2022. Stem Cell Res Ther. 13:247. PubMed Diao J, et al. 2018. J Immunol. 201:1306. PubMed Mincham KT, et al. 2021. Front Immunol. 11:601494. PubMed\u003cbr\u003e\nRRID: AB_2629714 (BioLegend Cat. No. 152402)\u003cbr\u003e\nStructure: Ig superfamily, associates with CD21 and CD81, 95 kD.\u003cbr\u003e\nDistribution: Pro-B cells to mature B cells (during development), follicular dendritic cells.\u003cbr\u003e\nFunction: Modulates B cell activation and differentiation.\u003cbr\u003e\nLigand\/Receptor: CD21, CD81, Leu-13.\u003cbr\u003e\nCell Type: B cells, Dendritic cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341. 2. Krop I, et al. 1996. Eur. J. Immunol. 26:238. 3. Krop I, et al. 1996. J. Immunol. 157:48. 4. Tedder TF, et al. 1994. Immunol. Today 15:437.\u003cbr\u003e\nGene ID: 12478\u003cbr\u003e\nUniProt: View information about CD19 on UniProt.org\u003cbr\u003e\nClone: 1D3\/CD19\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: B4, CVID3\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860852232361,"sku":"152402","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-152402","provider":"Iright","version":"1.0","type":"link"}