{"product_id":"biolegend-152511","title":"Biolegend, 152511, APC\/Fire™ 750 anti-mouse CD191 (CCR1) Antibody, 25μg","description":"\u003cp\u003eCD191, also known as CCR1, is a seven transmembrane G protein coupled receptor. It is involved in protecting the host from inflammatory responses and viral\/parasite invasion, ligands include macrophage inflammatory protein 1 alpha (MIP-1 alpha, ), regulated on activation normal T expressed and secreted protein (RANTES, CCL5), monocyte chemoattractant protein 3 (MCP-3, CCL7), and myeloid progenitor inhibitory factor-1 (MPIF-1, CCL23).\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CCR1-transfectants.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC\/Fire™ 750 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 5.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.* APC\/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nRRID: AB_2904293 (BioLegend Cat. No. 152511) AB_2904293 (BioLegend Cat. No. 152512)\u003cbr\u003e\nStructure: 41KD, seven transmembrane protein.\u003cbr\u003e\nDistribution: Macrophages, monocytes, neutrophils and eosinophils.\u003cbr\u003e\nFunction: Regulating migration of cells in response to CCL3, CCL5, CCL7 and CCL23.\u003cbr\u003e\nLigand\/Receptor: CCL3, CCL5, CCL7 and CCL23.\u003cbr\u003e\nCell Type: Eosinophils, Macrophages, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Cytokine\/Chemokine Receptors, GPCR\u003cbr\u003e\nAntigen References: 1. Lionakis MS, et al. 2012. PLoS Pathog. 8:e1002865. 2. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194. 3. Gong X, et al. 1997. J. Biol. Chem. 272:11682. 4. Daugherty BL, Springer MS. 1997. Genomics. 41:294. 5. Pakianathan DR, et al. 1997. Biochemistry 36:9642.\u003cbr\u003e\nGene ID: 12768\u003cbr\u003e\nUniProt: View information about CD191 on UniProt.org\u003cbr\u003e\nClone: S15040E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866215895209,"sku":"152511","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-152511","provider":"Iright","version":"1.0","type":"link"}