{"product_id":"biolegend-152708","title":"Biolegend, 152708, Alexa Fluor® 594 anti-mouse Lypd8 Antibody, 100μg","description":"\u003cp\u003eLy6\/PLAUR domain containing 8 (Lypd8) is a 100-120 kD GPI-anchored glycoprotein and a member of the Ly6\/PLAUR family. Lypd8 is highly expressed on epithelial cells from intestinal lumen, where it prevents bacterial invasion by inhibiting bacterial motility by binding to flagella.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Mouse Lypd8-transfected cells.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: IHC-F - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a concentration of 5 µg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nApplication Notes: This clone does not recognize Lypd8 from BALB\/c mice.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Okumura R, et al. 2016. Nature 532:117.\u003cbr\u003e\nRRID: AB_2721384 (BioLegend Cat. No. 152707) AB_2721385 (BioLegend Cat. No. 152708)\u003cbr\u003e\nStructure: GPI-anchored, glycoprotein, 100-120 kD.\u003cbr\u003e\nDistribution: Epitelials cells in cecum and large intestine.\u003cbr\u003e\nFunction: Inhibits bacterial motility by binding to flagella.\u003cbr\u003e\nCell Type: Epithelial cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nAntigen References: 1. Okumura R, et al. 2016. Nature 532:117. 2. Loughner CL, et al. 2016. Hum. Genomics 10:10.\u003cbr\u003e\nGene ID: 70163\u003cbr\u003e\nUniProt: View information about Lypd8 on UniProt.org\u003cbr\u003e\nClone: SA025A4\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ly6\/PLAUR domain containing 8\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866279465129,"sku":"152708","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-152708","provider":"Iright","version":"1.0","type":"link"}