{"product_id":"biolegend-158802","title":"Biolegend, 158802, Purified anti-mouse CD129 (IL-9R) Antibody, 500μg","description":"\u003cp\u003eCD129 is the ligand binding subunit of IL-9 receptor (IL-9R or IL-9Rα). It is a type I transmembrance glycoprotein belonging to the hematopoientin receptor superfamily. The signal transducing subunit is common gamma chain (γc, CD132), which is shared with receptors for IL-2, IL-4, IL-7, and IL-21. The mouse IL-9R has 468aa and is about 52.2 kD. Besides modulating immune response, signals through IL-9 and IL-9R are also invoved in allergy and inflammatory disorders.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse IL-9R transfectants\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nProduct Citations: Pajulas, A. et al. 2023. Mucosal Immunology. 16(4), 432-445. PubMed\u003cbr\u003e\nRRID: AB_2832565 (BioLegend Cat. No. 158802)\u003cbr\u003e\nStructure: Type I transmemberane glycoprotein; WSXWS motif\u003cbr\u003e\nDistribution: Subset of B cells, mast cells\u003cbr\u003e\nFunction: Binding IL-9; activate JAK-STAT signaling\u003cbr\u003e\nInteraction: Common gamma chain (CD132)\u003cbr\u003e\nLigand\/Receptor: IL-9\u003cbr\u003e\nCell Type: B cells, Eosinophils, Mast cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immuno-Oncology, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Cytokine\/Chemokine Receptors, Growth Factors\u003cbr\u003e\nAntigen References: Druez C, et al. 1990. J Immunol. 145:2494-9. Renauld JC, et al. 1992. Proc Natl Acad Sci USA. 89:5690. Takatsuka S, et al. 2018. Nat Immunol. 19:1025-34.\u003cbr\u003e\nGene ID: 16199\u003cbr\u003e\nUniProt: View information about CD129 on UniProt.org\u003cbr\u003e\nClone: S18011D\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9Rα\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866243518633,"sku":"158802","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-158802","provider":"Iright","version":"1.0","type":"link"}