{"product_id":"biolegend-166005","title":"Biolegend, 166005, FITC anti-mouse CD52 Antibody, 25μg","description":"\u003cp\u003eCD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages\/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)\/lymphoma and immunosuppression.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nRRID: AB_3675017 (BioLegend Cat. No. 166005) AB_3675017 (BioLegend Cat. No. 166006)\u003cbr\u003e\nStructure: CD52 is a peptide of 12 amino acids, anchored to glycosylphosphatidylinositol (GPI).\u003cbr\u003e\nDistribution: Expressed on lymphohematopoietic tissues, including thymus, spleen, and bone marrow, but not in liver, kidney, and brain\u003cbr\u003e\nFunction: Promote cell-mediated killing (antibody-dependent cellular cytotoxicity)\u003cbr\u003e\nCell Type: Dendritic cells, Lymphocytes, Mesenchymal Stem Cells, Monocytes, Thymocytes\u003cbr\u003e\nBiology Area: Cell Adhesion\u003cbr\u003e\nMolecular Family: Adhesion Molecules\u003cbr\u003e\nAntigen References: Gudrun R, et al. 2002. Blood. 101:1422.\u003cbr\u003e\nGene ID: 23833\u003cbr\u003e\nUniProt: View information about CD52 on UniProt.org\u003cbr\u003e\nClone: S19014A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CAMPATH-1 antigen\u003cbr\u003e\nIsotype: Rat IgM, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866259771561,"sku":"166005","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-166005","provider":"Iright","version":"1.0","type":"link"}