{"product_id":"biolegend-250808","title":"Biolegend, 250808, APC anti-rat CD335 (NKp46) Antibody, 100μg","description":"\u003cp\u003eCD335, also known as NKp46, is a glycoprotein of the natural cytotoxicity receptor (NCR) family with 2 Ig-like domains and a short cytoplasmic tail. CD335 expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. NKp46 functions as a cytotoxicity triggering receptor.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Rat\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Rat NKp46 ectodomain recombinant protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nRRID: AB_2734244 (BioLegend Cat. No. 250807) AB_2734245 (BioLegend Cat. No. 250808)\u003cbr\u003e\nStructure: Single-pass type I membrane protein, 46 kD; belongs to the natural cytotoxicity receptor (NCR) family; contains 2 Ig-like (immunoglobulin-like) domains.\u003cbr\u003e\nDistribution: Mature and immature NK cells, subset of NKT cells, but not on CD1d-restricted NKT cells.\u003cbr\u003e\nFunction: NK cells activation\u003cbr\u003e\nLigand\/Receptor: Viral hemagglutinins, heparan sulfate proteoglycans\u003cbr\u003e\nCell Type: NK cells, NKT cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Westgaard IH, et al. 2004. J. Leuko. Biol. 76:1200. Falco M, et al. 1999. Immunol. Lett. 68:411. Caligiuri MA. 2008. Blood. 112:461.\u003cbr\u003e\nGene ID: 117547\u003cbr\u003e\nUniProt: View information about CD335 on UniProt.org\u003cbr\u003e\nClone: WEN23\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: NCR1, NKP46, LY94\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864089284777,"sku":"250808","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-250808","provider":"Iright","version":"1.0","type":"link"}