{"product_id":"biolegend-315405","title":"Biolegend, 315405, Purified anti-human CD102 (ICAM-2) Antibody, 100μg","description":"\u003cp\u003eCD102, also known as Intercellular Adhesion Molecule-2, or ICAM-2, is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a\/CD18), DC-SIGN, and MAC-1.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human CD102 (ICAM-2) recombinant protein fragment\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Flow cytometry testing showed that clone W22039A does not affect the binding of clones W22038F and CBR-IC2\/2 on target cells.\u003cbr\u003e\nRRID: AB_3675043 (BioLegend Cat. No. 315405)\u003cbr\u003e\nStructure: 55 kD type I transmembrane glycoprotein, Ig superfamily\u003cbr\u003e\nDistribution: Vascular endothelial cells, lymphocytes, monocytes, platelets\u003cbr\u003e\nFunction: Adhesion, costimulation\u003cbr\u003e\nLigand\/Receptor: LFA-1, DC-SIGN, MAC-1\u003cbr\u003e\nCell Type: Epithelial cells, Lymphocytes, Monocytes, Platelets\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Weber KSC, et al. 2004. Inflammation. 28:177-88. Barclay A, et al. 1997. The Leukoycte Antigen FactsbookAcademic Press. Casasnovas JM, et al. 1999. P Natl Acad Sci. USA. 96:3017. Diamonds MS, et al. 1990. J Cell Biol. 111:3129-39.\u003cbr\u003e\nGene ID: 3384\u003cbr\u003e\nUniProt: View information about CD102 on UniProt.org\u003cbr\u003e\nClone: W22039A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Intercellular Adhesion Molecule-2, ICAM-2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866432065705,"sku":"315405","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-315405","provider":"Iright","version":"1.0","type":"link"}