{"product_id":"biolegend-315505","title":"Biolegend, 315505, Purified anti-human CD26 Antibody, 100μg","description":"\u003cp\u003eCD26, also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV), is a 110 kD type II membrane protein. It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human DPP4 (AA 41-766)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_3717110 (BioLegend Cat. No. 315505)\u003cbr\u003e\nStructure: Peptidases and ectoenzyme families, type II glycoprotein, 110 kD\u003cbr\u003e\nDistribution: Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages\u003cbr\u003e\nFunction: Dipeptidyl peptidase, T cell costimulation, HIV entry\u003cbr\u003e\nLigand\/Receptor: Adenosine-deaminase, collagen\u003cbr\u003e\nCell Type: B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Kameoka J, et al. 1993. Science. 261:466-9. Dang N, et al. 1990. J. Exp. Med. 172:649-52.\u003cbr\u003e\nGene ID: 1803\u003cbr\u003e\nUniProt: View information about CD26 on UniProt.org\u003cbr\u003e\nClone: A21111E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Dipeptidyl peptidase-4, adenosine deaminase complexing protein 2, ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5, DPP4\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866075091113,"sku":"315505","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-315505","provider":"Iright","version":"1.0","type":"link"}