{"product_id":"biolegend-324504","title":"Biolegend, 324504, Alexa Fluor® 647 anti-human IgD Antibody, 100μg","description":"\u003cp\u003eIgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a\/CD79b (Igα\/Igβ) heterodimer, resulting in the activation of the B cell.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Full length human IgD recombinant protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: IHC-P - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration of 10.0 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm \/ 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nRRID: AB_3097334 (BioLegend Cat. No. 324503) AB_3097334 (BioLegend Cat. No. 324504)\u003cbr\u003e\nStructure: Exists in a transmembranal and a soluble form\u003cbr\u003e\nDistribution: Naïve B cells\u003cbr\u003e\nFunction: Antigen binding, B cell activation\u003cbr\u003e\nInteraction: The CD79a\/CD79b heterodimer\u003cbr\u003e\nMolecular Family: Immune Checkpoint Receptors, Innate Immune Signaling\u003cbr\u003e\nAntigen References: Geisberger R, et al. 2006. Immunology 118:429-37. Weller S, et al. 2005. Eur J Immunol. 35:2789-92. Brandtzaeg P \u0026amp; Johansen FE. 2005. Immunol Rev. 206:32-63.\u003cbr\u003e\nGene ID: 3495\u003cbr\u003e\nUniProt: View information about IgD on UniProt.org\u003cbr\u003e\nClone: W18340A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ig delta chain C region\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866339102889,"sku":"324504","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-324504","provider":"Iright","version":"1.0","type":"link"}