{"product_id":"biolegend-324902","title":"Biolegend, 324902, Purified anti-human CD14 Recombinant Antibody, 100μg","description":"\u003cp\u003eCD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone QA18A04 antibody is able to completely block binding of clone HCD14 on target cells.\u003cbr\u003e\nRRID: AB_2888828 (BioLegend Cat. No. 324902)\u003cbr\u003e\nStructure: GPI-linked membrane glycoprotein, 53-55 kD\u003cbr\u003e\nDistribution: Monocytes, macrophages, granulocytes\u003cbr\u003e\nFunction: LPS receptor\u003cbr\u003e\nLigand\/Receptor: LPS\u003cbr\u003e\nCell Type: Granulocytes, Macrophages, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Stocks SC, et al. 1990. Biochem J. 268:275-80. Wright SD, et al. 1990. Science. 249:1431-3.\u003cbr\u003e\nGene ID: 929\u003cbr\u003e\nUniProt: View information about CD14 on UniProt.org\u003cbr\u003e\nClone: QA18A04\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: LPS receptor\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866177949865,"sku":"324902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-324902","provider":"Iright","version":"1.0","type":"link"}