{"product_id":"biolegend-331405","title":"Biolegend, 331405, FITC anti-human TCR Vδ2 Antibody, 25tests","description":"\u003cp\u003eThe Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ\/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ\/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ\/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Chimpanzee\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Rojas RE, et al. 2005. J. Infect. Dis. 192:1806. Correia DV, et al. 2011. Blood 118:992. (FC) PubMed\u003cbr\u003e\nProduct Citations: Jeon SB, et al. 2023. Cell Prolif. 56:e13366. PubMed Zarobkiewicz M, et al. 2022. J Clin Med. 11: . PubMed Wragg KM, et al. 2020. Cell Reports. 31(11):107773. PubMed Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed Jeon SB, et al. 2022. Int J Stem Cells. Online ahead of print. PubMed Garrido C, et al. 2018. JCI Insight. 3:e120121. PubMed Vyborova A, et al. 2022. Front Immunol. 13:915366. PubMed Krishnan S, et al. 2021. Clin Exp Immunol. 203:458. PubMed Yin S, et al. 2015. Sci Rep. 5: 14432. PubMed Wang Z, et al. 2018. Front Immunol. 9:1239. PubMed Tsai C, et al. 2015. J Immunol. 194:3890. PubMed\u003cbr\u003e\nRRID: AB_1089231 (BioLegend Cat. No. 331405) AB_1089230 (BioLegend Cat. No. 331406)\u003cbr\u003e\nStructure: Ig superfamily member, TCR γ\/δ with CD3 forms the CD3\/TCR complex\u003cbr\u003e\nDistribution: Expressed on majority of peripheral γ\/δT cells\u003cbr\u003e\nFunction: Antigen recognition, T cell activation\u003cbr\u003e\nLigand\/Receptor: Peptide bound to MHC\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Scotet E, et al. 2005. Immunity 22:71. 2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144.\u003cbr\u003e\nGene ID: 6964\u003cbr\u003e\nUniProt: View information about TCR Vdelta2 on UniProt.org\u003cbr\u003e\nClone: B6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor V δ 2, TRDV2, TCRDV102S1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862893220009,"sku":"331405","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-331405","provider":"Iright","version":"1.0","type":"link"}